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In the event the response to an opioid antagonist is suboptimal or only quick in character, administer additional antagonist as directed because of the solution’s prescribing information and facts. The respiratory depressant effects of promethazine are usually not reversed by opioid antagonists, including naloxone.Promethazine Hydrochloride and C

Daily life-Threatening Respiratory Depression Tell clients of the chance of life-threatening respiratory despair, like details that the danger is biggest when starting up promethazine HCl and codeine phosphate oral Answer and that it might arise even at recommended dosages [see Warnings and Safety measures (five.Check out the label on the prescript